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  1. INTRODUCTION. Sepsis is life threatening organ dysfunction secondary to a dysregulated host response to infection (1). Sepsis is the leading cause of death among critically ill patients in the United States with at least 270,000 patients dying annually (2).

  2. Abstract. Objective: Sepsis is responsible for a massive burden of disease, with a global estimate of 48.9 million cases resulting in approximately 11 million deaths annually. Survivors of sepsis may also experience long-term impairments that can persist for years after hospital discharge.

  3. Among patients with sepsis, a prior history of chronic alcohol abuse confers a significant increase in the likelihood of respiratory dysfunction and development of acute respiratory distress syndrome (ARDS).

  4. Published data on the clinical impact of alcoholic aetiology and alcohol abuse on infection-related complications (acute kidney injury (AKI), severe sepsis, and ACLF) and short-term mortality in cirrhosis are controversial.

  5. 20 Οκτ 2022 · Symptoms of post-sepsis syndrome can develop within 90 days of recovering from sepsis and include fatigue, joint pain, and panic attacks. The symptoms can last anywhere from six to 18 months. This article discusses the frequent and rare symptoms associated with post-sepsis syndrome and the complications that may develop because of it.

  6. The diagnosis of sepsis in the context of Alcohol-related Liver Disease is challenging. Moreover, the use of classical acute-phase serum proteins (e.g., C-reactive protein and procalcitonin) has several limitations in this setting. The early administration of an adequate antibiotic treatment is pivotal.

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