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25 Ιαν 2023 · Rheumatoid arthritis is an autoimmune disease. Normally, your immune system helps protect your body from infection and disease. In rheumatoid arthritis, your immune system attacks healthy tissue in your joints. It can also cause medical problems with your heart, lungs, nerves, eyes and skin.
29 Αυγ 2023 · Severe arthritis, particularly if it affects your hands or arms, can make it difficult for you to do daily tasks. Arthritis of weight-bearing joints can keep you from walking comfortably or sitting up straight. In some cases, joints may gradually lose their alignment and shape. By Mayo Clinic Staff.
13 Οκτ 2019 · Disease characteristics and achievement of remission were compared between seropositive (rheumatoid factor positive and/or anti–citrullinated peptide antibody positive) and seronegative (rheumatoid factor negative/anti–citrullinated peptide antibody negative) patients.
25 Ιαν 2023 · Symptoms & causes Doctors & departments. This chronic inflammatory disorder can affect more than just your joints. It can also damage your skin, eyes, lungs, heart and blood vessels.
9 Μαρ 2010 · In some patients with early rheumatoid arthritis, clinical examination may not yield evidence of synovitis, in particular in those who test seronegative for the disease. Advanced imaging techniques such as high-resolution ultrasonography and magnetic resonance imaging can be useful in such cases.
When a patient tests negative for RF and anti-CCP antibodies, yet they still display strong symptoms consistent with rheumatoid arthritis, they are given a diagnosis of seronegative rheumatoid arthritis. The term seronegative means they don’t possess the antibodies that seropositive patients do.
The management of rheumatoid arthritis has changed considerably during the past 15 years. Current strategies emphasize the need for early diagnosis and therapeutic intervention based on the use of disease-modifying antirheumatic drugs.
