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This serum iron study panel may help diagnose iron deficiency or overload. Because ferritin level can be affected by clinical conditions other than iron disorders, the measurement of transferrin saturation-calculated from serum iron level and total iron binding capacity (TIBC)-in the same serum specimen may facilitate the diagnosis of iron ...
Serum iron studies are useful in the evaluation of disorders of iron metabolism, particularly iron deficiency and iron excess. Iron studies are best performed when the patient is fasting in the morning and has abstained from medications that may influence iron balance.
The total iron binding capacity (TIBC) measures the amount of iron that would appear in blood if all the transferrin were saturated with iron. It is an indirect measurement of transferrin concentrations but expressed as an iron measurement.
Serum iron is a measure of circulating iron, most of which is bound to transferrin. The serum iron level is low in iron deficiency and inflammatory anaemia because it depends on efficient recycling of iron through macrophages and the bone marrow.
ANA Screen,IFA, with Reflex to Titer and Pattern -. This immunofluorescence assay (IFA) is often ordered as part of an initial diagnostic evaluation of individuals with clinical suspicion of autoimmune diseases associated with antinuclear antibodies (ANAs).
To obtain the percent saturation, the serum iron is divided by the TIBC which gives the actual amount of saturated transferrin. The percent saturation is low in iron deficiency and high in iron storage diseases.
21 Απρ 2023 · The laboratory evaluation for individuals with clinical suspicion of these autoimmune diseases often begins with an ANA screen. Knowing the ANA titer can be helpful in interpreting positive ANA results.
