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  1. 1 Οκτ 2024 · Each pathway map is identified by the combination of 2-4 letter prefix code and 5 digit number (see KEGG Identifier). The prefix has the following meaning: map. manually drawn reference pathway.

    • Genes

      KEGG GENES is a collection of genes and proteins in complete...

    • Network

      KEGG NETWORK represents a renewed attempt by KEGG to capture...

    • Kegg Compound Database

      KEGG COMPOUND is one of the four original databases,...

    • Disease

      The Human Diseases category of the KEGG PATHWAY database is...

    • Orthology (Ko)

      The KO (KEGG Orthology) database is a database of molecular...

    • Brite

      KEGG BRITE is a collection of hierarchical classification...

    • Kegg Objects

      KEGG objects are biological entities from molecular to...

    • Drug

      KEGG DRUG is a comprehensive drug information resource for...

  2. 31 Οκτ 2019 · Here, we designed a web knowledgebase, the Signaling Pathways Project (SPP), which incorporates community classifications of signaling pathway nodes (receptors, enzymes, transcription...

  3. The KEGG PATHWAY database is a collection of manually drawn graphical diagrams, called KEGG pathway maps, for metabolic pathways, signaling pathways, pathways involved in various cellular processes and organismal systems, and perturbed pathways associated with human diseases.

  4. The Signaling Pathways Project is a multi-omics knowledgemine based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of cellular receptors, enzymes and transcription factors.

  5. 31 Δεκ 2018 · Signaling pathways are the key biological mechanisms that transduce extracellular signals to affect transcription factor mediated gene regulation within cells.

  6. 25 Οκτ 2014 · Here we propose a simple probabilistic model in which signaling pathways are separated into elementary sub-pathways or signal transmission circuits (which ultimately trigger cell functions) and then transforms gene expression measurements into probabilities of activation of such signal transmission circuits.

  7. 20 Φεβ 2008 · While SPIKE's modeling scheme can accommodate data on any signaling pathway from any organism, at present the implemented DB supports data obtained only in human cells (as genes are associated with the human Entrez-Gene ID and are designated using their HGNC official symbol).

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