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16 Ιουν 2023 · Clinical manifestations – Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease with a wide range of clinical and serologic manifestations that can affect virtually any organ. The disease course is often marked by remissions and relapses and may vary from mild to severe.
- Daniel J Wallace, MD
Section Editor — Systemic Lupus Erythematosus Professor of...
- Benito-Garcia E, Schur Ph, Lahita R, American College of Rheumatology Ad Hoc Committee on Immunologic Testing Guidelines. Guidelines for Immunologic Laboratory Testing in The Rheumatic Diseases: anti-Sm and anti-RNP Antibody Tests. Arthritis Rheum 2004; 51:1030
Medline ® Abstract for Reference 52 of 'Clinical...
- Guidelines for Referral and Management of Systemic Lupus Erythematosus in Adults. American College of Rheumatology Ad Hoc Committee on Systemic Lupus Erythematosus Guidelines. Arthritis Rheum 1999; 42:1785
Systemic lupus erythematosus (SLE) is a multiorgan disease...
- Ehmke Ta, Cherian Jj, Wu Es, Et Al. Treatment of Osteonecrosis in Systemic Lupus Erythematosus: a Review. Curr Rheumatol Rep 2014; 16:441
The pathogenesis of ON is largely unknown; however, there...
- Aringer M, Costenbader K, Daikh D, Et Al. 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus. Arthritis Rheumatol 2019; 71:1400
In the validation cohort, the new criteria had a sensitivity...
- Gladman Dd, Hussain F, Ibañez D, Urowitz Mb. The Nature and Outcome of Infection in Systemic Lupus Erythematosus. Lupus 2002; 11:234
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- Nived O, Sturfelt G, Wollheim F. Systemic Lupus Erythematosus and Infection: a Controlled and Prospective Study Including an Epidemiological Group. Q J Med 1985; 55:271
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- Daniel J Wallace, MD
4 Αυγ 2023 · Introduction. Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with multisystemic involvement. The condition has several phenotypes, with varying clinical presentations from mild mucocutaneous manifestations to multiorgan and severe central nervous system involvement.
Systemic lupus erythematous (SLE) is a chronic autoimmune inflammatory disease characterized by autoantibodies directed against numerous self-nuclear antigens. Due to the heterogeneous nature of lupus, it has been challenging to identify markers that are sensitive and specific enough for its diagnosis and monitoring.
21 Αυγ 2021 · Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by antibodies to nuclear and cytoplasmic antigens, multisystem inflammation, protean clinical manifestations, and...
5 Οκτ 2023 · Systemic lupus erythematosus (SLE) is a generalised disorder that can affect any system. Symptoms and signs may accumulate over time. The diagnosis is made using 2019 criteria recommended by the American College of Rheumatology and the European League Against Rheumatology. Treatments for mild to moderate serositis or arthritis include ...
21 Οκτ 2022 · Imaging tests. If your doctor suspects that lupus is affecting your lungs or heart, he or she may suggest: Chest X-ray. An image of your chest may reveal abnormal shadows that suggest fluid or inflammation in your lungs.
ANA testing is a recommended initial screening test for SLE. However, ANAs are not specific for SLE and are seen in a variety of other connective tissue diseases, some infections, and malignancies, and are detected in elderly patients and even in some healthy individuals.
