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  1. 4 Αυγ 2023 · Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with multisystem involvement and is associated with significant morbidity and mortality.

  2. 5 Οκτ 2023 · Systemic lupus erythematosus (SLE) is a generalised disorder that can affect any system. Symptoms and signs may accumulate over time. The diagnosis is made using 2019 criteria recommended by the American College of Rheumatology and the European League Against Rheumatology.

  3. 16 Ιουν 2023 · Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown cause that can affect virtually any organ of the body. Immunologic abnormalities, especially the production of a number of antinuclear antibodies (ANA), are a prominent feature of the disease.

  4. 21 Οκτ 2022 · The most common signs and symptoms include: Fatigue. Fever. Joint pain, stiffness and swelling. Butterfly-shaped rash on the face that covers the cheeks and bridge of the nose or rashes elsewhere on the body. Skin lesions that appear or worsen with sun exposure.

  5. 21 Αυγ 2021 · Practice Essentials. Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by antibodies to nuclear and cytoplasmic antigens, multisystem inflammation, protean clinical...

  6. Joint manifestations. Joint symptoms, ranging from intermittent arthralgias to acute polyarthritis, occur in about 90% of patients and may precede other manifestations by years. Most lupus polyarthritis is nondestructive and nondeforming.

  7. 22 Ιαν 2022 · Systemic lupus erythematosus (SLE) is a complicated life-threatening autoimmune disease characterized by systemic organ damage and a flare-remission pattern. The pathophysiology of SLE involves genetic predisposition, immune dissonance, epigenetic dysregulation, and dysbiosis of microbiota.

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