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12 Φεβ 2024 · Pregnancy Considerations: Clinicians should weigh the risks and benefits when considering sodium bicarbonate during pregnancy, as comprehensive human data is unavailable. There is a potential risk of fluid retention based on the drug's mechanism.
1 Μαΐ 2019 · We hypothesise that supplementation with preoperative sodium bicarbonate infusion as an acid buffer among patients with OL can reduce maternal acidosis at 1 hour after administration, while their newborns in the bicarbonate group will have less acidosis in cord blood at birth.
26 Αυγ 2024 · Our results indicate that current reference guides for the safe use of drugs during pregnancy are less scientific and reliable, and there are considerable discrepancies in recommendations from different reference guides concerning drug use during pregnancy.
9 Φεβ 2021 · We hypothesized that 4.2 g (50 mmol/L) of sodium bicarbonate administered as a single intravenous dose in the preoperative period could reduce the maternal blood lactate at one hour after administration compared to normal saline alone.
Smaller meals, not eating late at night, elevation of the head of the bed and avoiding foods and mediations causing heartburn usually relieve the mild symptoms seen in early pregnancy. Chewing gum stimulates the salivary glands and can help neutralize acid.
Pharmacological therapy for CVD during pregnancy is challenging because the pharmacokinetics of a drug may change throughout gestation. The majority of data on the safety of medication use during pregnancy relies on observational studies and expert opinion.
9 Φεβ 2021 · Objective: To determine the effect and safety of a single-dose preoperative infusion of sodium bicarbonate on maternal and fetal blood lactate and clinical outcomes among women with obstructed labour (OL) in Mbale hospital. Methods: We conducted a double blind, randomised controlled trial from July 2018 to September 2019.
