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Abstract. Solubility, bioavailability, permeation, polymorphism, and stability concerns associated to solid-state pharmaceuticals demand for effective solutions. To overcome some of these drawbacks, ionic liquids (ILs) have been investigated as solvents, reagents, and anti-solvents in the synthesis and crystallization of active pharmaceutical ...
Liquid—liquid extraction is a unit operation based on differential solubility of a consolute in two immiscible solvents. This separation technique, also known as solvent extraction, has many successful applications in the pharmaceutical industry because of its...
10 Ιουλ 2021 · Ionic liquids and deep eutectic solvents have a number of properties that make them desirable for use in biomedical applications. The selection of ions has a strong impact on the physico-chemical properties and biological outcome of the ionic liquids.
22 Ιαν 2024 · Ionic liquids can be used as (i) green solvents or catalysts in drug synthesis; (ii) extraction solvents, mobile phase additives and reagents for the modification/functionalization of stationary phases in drug analysis; (iii) solubilizer for insoluble drugs; (iv) crystallization media for effective control of crystal morphology and improvement ...
Ionic liquids (ILs) have been used as solvents or materials, or both, in many applications, including pharmaceutics and medicine due to their exceptional properties consisting of the combination of “green” properties with tunable physicochemical and biological properties.
One of the main applications of ionic liquids in drug discovery is the development of new solvents for chemical synthesis. ILs can be used as solvents for various reactions, including organic synthesis, and can also be used to enhance the solubility of compounds in aqueous media, which then produce it easier to purify and isolate compounds.
2 Αυγ 2021 · Due to their various applicability, ILs emerge as a future trend of solvents for the process of extraction and electrochemical reactions, catalysis, rapid drug delivery, etc. and further utilized to yield novel drugs by enhancing their solubilities in different solvent mixtures.