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Statins have long been used for the protection against coronary artery disease (CAD). Their beneficial effect apart from cholesterol reduction lies in their pleiotropic properties.
3 Απρ 2018 · Randomized trial of the effects of cholesterol-lowering with simvastatin on peripheral vascular and other major vascular outcomes in 20,536 people with peripheral arterial disease and other high-risk conditions.
10 Νοε 2021 · Coronary CTA has improved clinicians' ability to treat patients with coronary artery disease. Statin therapy is associated with reduced plaque progression, decrease in MACE, but increase in coronary calcium score.
6 Μαρ 2024 · Statins are drugs that can lower your cholesterol. They work by blocking a substance that your body needs to make cholesterol. Lowering cholesterol isn't the only benefit of taking a statin. These medicines also have been linked to a lower risk of heart disease and stroke. Statins also may help reduce the risk of certain blood clots.
1 Οκτ 2022 · Statins continue to be a first-line treatment for many people at risk of heart attacks and strokes. They help reduce cholesterol levels, reduce plaque build-up, and protect against plaque rupturing, fight inflammation, and have minimal, if any, side effects for most people.
Cardiovascular disease (CVD) is highly prevalent and the leading cause of morbidity and mortality in the US. Statins are used to prevent CVD-associated morbidity and mortality because of their positive effects on lipid profiles as well as anti-inflammatory and other plaque-stabilization effects.
Statin drugs are often prescribed to safely lower the risk of heart attacks, stroke and hardening of the arteries. What exactly are these drugs and how do they work?
