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17 Μαρ 2019 · 9. Statin therapy is first-line treatment for primary prevention of ASCVD in patients with elevated low-density lipoprotein cholesterol levels (≥190 mg/dL), those with diabetes mellitus, who are 40 to 75 years of age, and those determined to be at sufficient ASCVD risk after a clinician–patient risk discussion. 10.
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e596 September 10, 2019 Circulation. 2019;140:e596–e646....
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29 Φεβ 2024 · Statin medications are used in the management of hypercholesteremia. Statins are inhibitors of hydroxymethylglutaryl-CoA reductase enzyme and lower total cholesterol, low-density lipoprotein (LDL), and triglyceride concentrations.
6 Μαρ 2024 · Statins are drugs that can lower your cholesterol. They work by blocking a substance that your body needs to make cholesterol. Lowering cholesterol isn't the only benefit of taking a statin. These medicines also have been linked to a lower risk of heart disease and stroke. Statins also may help reduce the risk of certain blood clots.
Four Statin Benefit Groups: Secondary ASCVD Prevention. Clinical ASCVD: Figure 1 ................................................................................. 8. Criteria for Very High Risk ASCVD ..................................................................... 9. Severe Hypercholesterolemia (LDL-C ≥190)
2 Απρ 2002 · When one of these plaques tears or ruptures, a blood clot forms that may block the vessel completely and lead to a heart attack (also called a myocardial infarction, or MI, in medical terminology). One of the key risk factors for the development of atherosclerosis is high cholesterol.
29 Νοε 2023 · Statins work to lower LDL levels. This slows the buildup of cholesterol in your arteries. Statins also reduce inflammation in artery walls. If you do have plaque buildup inside your arteries, statins can help prevent them from breaking open and leading to blood clots.
Statins have long been used for the protection against coronary artery disease (CAD). Their beneficial effect apart from cholesterol reduction lies in their pleiotropic properties.