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21 Σεπ 2001 · Supercoiling provides a significant amount of free energy to DNA molecules and, inside cells, this can be used to drive structural transitions and other metabolic processes that would normally...
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Supercoiling provides a significant amount of free energy to...
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16 Φεβ 2021 · Here authors use atomic force microscopy and atomistic molecular dynamics simulations, to resolve structures of negatively-supercoiled DNA minicircles at base-pair resolution.
28 Σεπ 2021 · DNA in cells is supercoiled and constrained into loops and this supercoiling and looping influence every aspect of DNA activity. We show here that negative supercoiling transmits...
12 Οκτ 2015 · It is discovered that the underlying DNA sequence directly encodes the structure of supercoiled DNA by pinning plectonemes at specific positions, and a physical model is developed that predicts the level of plect oneme pinning, in excellent agreement with the data.
1 Ιουλ 1986 · This article reviews recent advances in our knowledge of Supercoiled DNA such as topology, energetic, and physicochemical characteristics as well as the biological implications of this tertiary...
12 Οκτ 2015 · Nature Communications - DNA supercoiling strongly affects its metabolism. By electron cryo-tomography, biochemical assays and molecular dynamics simulations, here the authors show that...
18 Ιουλ 2019 · Policing of the local and global supercoiling of DNA by topoisomerases helps to sustain the major DNA-based transactions by eliminating barriers to the movement of transcription complexes and replisomes.
