Αποτελέσματα Αναζήτησης
This review examines the biological, pathological and clinical evidence of SV40 pathogenesis and discusses future directions needed to define an etiologic role for the virus in some of these devastating diseases.
9 Ιουλ 2007 · Simian virus 40 (SV40) is a monkey virus that was administered to human populations by contaminated vaccines which were produced in SV40 naturally infected monkey cells.
1 Μαρ 2022 · The extensive poliovirus vaccination programs of the late 1950s and early 1960s lead to the accidental infection of millions of individuals with an unknown virus (SV40) possessing cancer-causing potential. This mistake sparked a massive research enterprise to...
acteristic cytopathic e•ects in green monkey cells. These authors demonstrated that this virus, which was called SV40, contaminated both the Salk and the Sabin poliovaccines.
5 Ιαν 2004 · Simian virus 40 (SV40) is a monkey virus that was introduced in the human population by contaminated poliovaccines, produced in SV40-infected monkey cells, between 1955 and 1963. Epidemiological evidence now suggests that SV40 may be contagiously transmitted in humans by horizontal infection, independent of the earlier administration of SV40 ...
What is the behavior of SV40 in human cells? Does it cause or contribute to acute or chronic disease? Other comprehensive reviews have also addressed these issues, with a variety of emphases ( 8, 10, 52, 57, 107 ).
20 Ιαν 1999 · This review presents aspects of replication and cell transformation by SV40 and considers their implications for human infections and disease pathogenesis by the virus. Critical assessment of virologic and epidemiologic data suggests a probable causative role for SV40 in certain human cancers, but additional studies are necessary to prove etiology.
