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SV40 is an abbreviation for simian vacuolating virus 40 or simian virus 40, a polyomavirus that is found in both monkeys and humans. Like other polyomaviruses, SV40 is a DNA virus that sometimes causes tumors in animals, but most often persists as a latent infection.
1 Μαρ 2022 · Early studies of infants receiving contaminated oral poliovirus vaccine found that 15–20% of these children shed the SV40 virus in their stools for up to five weeks post-vaccination, strongly suggestive of an active infection.
Vaccine Ingredients: SV40. Polio vaccines used in the late 1950s and early 1960s were contaminated with a virus called simian virus 40 (SV40) present in monkey kidney cells used to grow the vaccine.
9 Ιουλ 2007 · It has been shown that some vaccine-derived SV40 genotypes overlap with those detected in monkey and in human populations, supporting the hypothesis that contaminated vaccines may play a role in the introduction of SV40 into the human population .
31 Ιουλ 2004 · However, two Merck researchers, Ben Sweet and Maurice Hilleman, soon identified the rhesus virus later named SV40—the carcinogenic agent that had eluded Eddy. In 1963, US authorities decided to switch to African green monkeys, which are not natural hosts of SV40, to produce polio vaccine.
23 Αυγ 2004 · Studies can be grouped into three categories based on their exposure definition of SV40 infection: (1) use of vaccination or birth cohorts as proxy variables for infection, (2) follow-up of...
20 Ιαν 1999 · SV40-neutralizing antibodies have been detected in individuals not exposed to contaminated polio vaccines. SV40 DNA has been identified in some normal human tissues, and there are accumulating reports of detection of SV40 DNA and/or T-ag in a variety of human tumors.
