Αποτελέσματα Αναζήτησης
2 Φεβ 2015 · Nucleotide synthesis is regulated by several critical transcription factors (cf. Table Table1), 1), MYC and Rb/E2F in particular, which if mutated or overexpressed are associated with transformation and uncontrolled proliferation leading to cancer .
- Figure3A 3A
Purine biosynthesis: synthesis of IMP. Various atoms of the...
- Figure1 1
De novo nucleotide biosynthesis: generation of activated...
- Figure5 5
Atom resolved tracing from glucose and glutamine into...
- (Figures2 2
Nucleotides are required for a wide variety of biological...
- Table1) 1
Nucleotides are required for a wide variety of biological...
- Figure3A 3A
8 Μαρ 2019 · Scheme showing a the network of reactions involving the simultaneous one-pot formation of glycosylation products (nucleotide, cyclic nucleotide and nucleosides) with three nucleobases (adenine ...
12 Αυγ 2019 · These 'free' daughter nuclides are no longer targeted to the tumour and can accumulate in normal tissue. In this paper, we used polymersomes as model carrier to evaluate the retention of recoiling daughters of 225 Ac in vivo, and assessed their suitability as therapeutic agents.
20 Ιουν 2016 · Focusing on the recent literature (since 2000), this review outlines the main synthetic approaches for the preparation of 5′-mono-, 5′-di-, and 5′-triphosphorylated nucleosides, also known as nucle...
30 Οκτ 2021 · The rapid development of radionuclide probes aids the diagnosis of breast cancer in various aspects. These probes target metabolism, amino acid transporters, cell proliferation, hypoxia, estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), gastrin-releasing peptide receptor (GRPR) and so on.
Nucleotide synthesis will be described below, but one of the fundamental requirements of the synthesis of either purines or pyrimidines is the need for a five-carbon sugar (ribose). This sugar is generated through glucose oxidation via the pentose phosphate pathway.
27 Οκτ 2021 · First of all, unlabeled small molecule precursors have the advantages of definite chemical structure, flexible modification space, controllable pharmacokinetic properties, non-immunogenicity, and ease of synthesis commonly involving solid-phase peptide synthesis.
