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  1. 9 Ιουν 2020 · Kuijpens et al. demonstrated that low levels of free T4 (fT4) are an independent risk factor for the development of breast cancer in peri- and post-menopausal women (risk of cancer in patients with low fT4 levels (≤10th percentile which is equivalent to ≤12.5 pmol/L, OR: 2.3; 95% CI: 1.2–4.6).

  2. 22 Ιουλ 2024 · Cai et al. demonstrated that serum levels of TSH and free T4 were significantly decreased in cortisol-producing adenomas (CPAs) as compared to healthy controls and asymptomatic adrenal incidentalomas. This study also revealed a negative association of cortisol, TSH, and T4 serum levels with CPAs.

  3. In the past, the usual treatment for thyroid cancer after thyroid surgery was to achieve TSH suppression with a low TSH. However, current American Thyroid Association guidelines for the management of thyroid cancer recommend a TSH target in the low normal range for most low risk thyroid cancers.

  4. There have been studies suggesting that higher levels of free T 4 in the blood may be associated with an increased risk of developing a solid cancers (for example, lung, breast, prostate, gastrointestinal (GI) cancers). Other studies have not agreed with this finding.

  5. 18 Σεπ 2020 · In this review, we will summarize population and case–control studies that investigated the relationship between hyperthyroidism, upper reference range TH levels, lower thyrotropin (TSH) levels, lower reference range TSH levels with cancer risk, cancer prognosis, and cancer outcome.

  6. 1 Απρ 2012 · Evidence Synthesis: In patients with nodular thyroid disease, the risk of thyroid malignancy increases with serum TSH, and even within normal ranges, higher TSH values are associated with a higher frequency and more advanced stage of thyroid cancer.

  7. 20 Σεπ 2020 · In this review, we will summarize population and case-control studies that investigated the relationship between hyperthyroidism, upper reference range TH levels, lower thyrotropin (TSH) levels, lower reference range TSH levels with cancer risk, cancer prognosis, and cancer outcome.

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