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T4 is the main form of thyroid hormone circulating in the blood. A Total T4 measures the bound and free hormone and can change when binding proteins differ (see above). A Free T4 measures what is not bound and able to enter and affect the body tissues. Tests measuring free T4 – either a free T4 (FT4) or free T4 index
1 Μαρ 2014 · TSH and Free T4 (FT4) are best suited to assess the thyroid function in a healthy population with no past medical history of thyroid disease.
1 Ιαν 2020 · Specific diagnostic categories for 14 tests, showing high free T4 and normal TSH. …
6 Δεκ 2023 · This means that very small changes in serum free T4 concentrations induce very large reciprocal changes in serum TSH concentrations. As a result, thyroid function is best assessed by measuring serum TSH, assuming steady-state conditions and the absence of pituitary or hypothalamic disease.
28 Μαΐ 2024 · Blood tests can measure the levels of TSH and the thyroid hormones triiodothyronine (T3) and thyroxine (T4). Abnormal TSH levels may be an early sign of thyroid problems. For this reason, it is common to only measure the TSH level at first.
There have been considerable improvements in assays for thyrotropin (TSH), free T4, and free T3 over the past 20 years. As a result, interpretation of thyroid function tests is now generally straightforward, and more than 90% of people investigated are diagnosed with normal thyroid gland function.
TSH levels are measured by a simple blood test that determines how much T4 the thyroid is being asked to make.1,3 The ranges below show where your TSH levels should be. Hyperthyroidism or suppressed TSH. 0.0-0.4. Normal range of TSH. 0.4-4.0. Mild hypothyroidism. 4.0-10.0. Hypothyroidism. 10+.