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1 Αυγ 2013 · Although there is strong evidence for the use of aspirin for secondary prevention of CVD (as noted in the 2013 ADA Standards of Care), aspirin use for primary prevention of CVD in patients with and without diabetes is less clear cut in light of the potential risks of therapy.
- Aspirin Therapy in Diabetes | Diabetes Care - American Diabetes Association
Use aspirin therapy as a primary prevention strategy in men...
- Aspirin Therapy in Diabetes | Diabetes Care - American Diabetes Association
Low-dose aspirin is a widely used agent for preventing cardiovascular disease, and various guidelines also recommend its use in subjects with diabetes. Several primary prevention aspirin trials- prior to 2000 suggested a reduction in myocardial infarction and stroke, although not mortality but at the cost of increased bleeding events.
Aspirin is the cornerstone of treatment in patients with cardiovascular disease, irrespective of diabetes status, being able to confer a 19% relative risk reduction per year in serious vascular events compared with placebo at long-term follow-up (6.7% vs 8.2% per year, p < 0.0001).
15 Δεκ 2010 · Low-dose aspirin therapy is reasonable in adults with diabetes and no history of vascular disease, whose 10-year risk of CHD events is greater than 10 percent, and who are not at increased risk...
1 Ιαν 2004 · Use aspirin therapy as a primary prevention strategy in men and women with type 1 diabetes at increased cardiovascular risk, including those over 40 years of age or who have additional risk factors (family history of CVD, hypertension, smoking, dyslipidemia, albuminuria).
Aspirin use among high-risk patients with diabetes and asymptomatic peripheral artery disease did not reduce the composite endpoint of fatal myocardial infarction or stroke, nonfatal myocardial infarction or stroke, or above-ankle amputation due to critical limb ischaemia. 14.
Aspirin is widely used in patients with established cardiovascular disease (CYD) to prevent major adverse cardiovascular events (MACEs). 1, 2 Diabetes mellitus (DM) is associated with a higher risk of CVD. 3, 4 While the use of aspirin therapy in DM has increased over time, the role of aspirin for the primary prevention of CVD in DM remains cont...
