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Thiocyanate is a competitive inhibitor of the sodium iodide symporter (NIS) at thiocyanate levels normally found in blood. Thereby, it worsens iodine deficiency by inhibition of thyroidal iodide accumulation and by inhibition of iodide transport into breast milk for infant nutrition.
10 Αυγ 2022 · Benedict’s Test is used to test for simple carbohydrates. The Benedict’s test identifies reducing sugars (monosaccharide’s and some disaccharides), which have free ketone or aldehyde functional groups.
Since thiocyanates will decrease iodide transport into the thyroid follicular cell, they will decrease the amount of thyroxine produced by the thyroid gland. As such, foodstuffs containing thiocyanate are best avoided by iodide deficient hypothyroid patients. [14]
31 Δεκ 2009 · Thiocyanate is a competitive inhibitor of the sodium iodide symporter (NIS) at thiocyanate levels normally found in blood. Thereby, it worsens iodine deficiency by inhibition of thyroidal iodide...
Thiocyanate is a competitive inhibitor of the sodium iodide transporter responsible for the accumulation of iodide in the thyroid gland and in breast milk. • Exposure to thiocyanate corresponds to a decrease in iodine intake. • In areas of low iodine intake, thiocyanate exposure increases the risk of dvelopmental and other iodine deficiency ...
The inhibitory action of thiocyanate on iodine uptake is due to a competitive effect of pseudohalide with the mechanism of iodide concentration. However, under experimental conditions, rather high plasma concentrations of thiocyanate are required for inhibiting iodine uptake by the thyroid gland.
Thiocyanate (SCN) functions in host defense as part of the secreted lactoperoxidase (LPO) microbicidal pathway. SCN is the preferred substrate for LPO-driven catalytic reduction of hydrogen peroxide (H2O2) forming hypothiocyanous acid (HOSCN).
