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13 Απρ 2019 · After shorter exposure to TiO 2 NPs (30 days), changes in heart rate (HR) and blood pressure (BP) could be noted. Savi et al. [ 73 ] discovered that intra-breath in vivo administration of the saline solution containing TiO 2 NPs (2 mg/kg) increased the rate of cardiac conduction, which results in increased likelihood of developing arrhythmia.
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26 Ιαν 2021 · Hydroxyl radicals (OH) are associated with titanium dioxide (TiO2) nanoparticle-induced cytotoxicity and oxidative DNA damage in fish cells. Mutation Research, Fundamental and Molecular Mechanisms of Mutagenesis.
31 Δεκ 2022 · TiO2 NPs and nanoparticle-derived titanium induce cardiac injury, endothelial dysfunction and increase blood pressure and heart rate.
3 Δεκ 2015 · After daily gastrointestinal administration of TiO2 NPs at 0, 2, 10, 50 mg/kg for 30 and 90 days, heart rate (HR), blood pressure, blood biochemical parameters and histopathology of cardiac tissues was assessed to quantify cardiovascular damage.
15 Απρ 2013 · Titanium dioxide (TiO 2) nanoparticles (NPs) are manufactured worldwide in large quantities for use in a wide range of applications. TiO 2 NPs possess different physicochemical properties compared to their fine particle (FP) analogs, which might alter their bioactivity.
Over the last decades, the exposure to titanium dioxide nanoparticles (TiO 2 NPs) has increased due to the wide application in industry, food adduct, medicine, cosmetic products, etc. Literature review showed that the TiO 2 NPs exert toxic effects on several organs. Methods.
10 Σεπ 2021 · In this study, different TiO 2 NPs exposure modes are discussed, and their toxicity mechanisms-evaluated in various in vitro and in vivo studies-are briefly described, considering the molecular interactions with human health and the environment.