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1. pubmed.ncbi.nlm.nih.gov › 36412248Role of topical spironolactone in the treatment of acne: A ... -...

   pubmed.ncbi.nlm.nih.gov › 36412248

   Oral spironolactone is used for treating acne vulgaris due to its antiandrogenic properties and inhibition of sebogenesis. Recent evidence shows that spironolactone in topical form has similar efficacy to its oral form with comparatively fewer adverse events associated with its use.

2. www.jaad.org › article › S0190-9622(21)00090-6Long-term use of spironolactone for acne in women: A case series...

   www.jaad.org › article › S0190-9622(21)00090-6

   Our findings highlight that long-term use of spironolactone improves clinical outcomes and is well tolerated for many adult women with acne. Given that spironolactone is prescribed 3 to 7 times less frequently than oral antibiotics for women with acne, increasing the use of spironolactone for women with acne may represent an opportunity to ...

3. www.jaad.org › article › S0190-9622%2823%2903389-3Guidelines of care for the management of acne vulgaris

   www.jaad.org › article › S0190-9622%2823%2903389-3

   This guideline presents 18 evidence-based recommendations and 5 good practice statements. Strong recommendations are made for benzoyl peroxide, topical retinoids, topical antibiotics, and oral doxycycline.

4. www.researchgate.net › publication › 364815809_Role_of_Topical_Spironolactone_inRole of Topical Spironolactone in the Treatment of Acne- A...

   www.researchgate.net › publication › 364815809_Role_of_Topical_Spironolactone_in

   28 Οκτ 2022 · Conclusion: Topical spironolactone yields better results than other first-line treatments for acne and displays fewer side effects. However, further large-scale clinical trials are required...

5. pmc.ncbi.nlm.nih.gov › articles › PMC8483163Treatment of Acne Vulgaris by Topical Spironolactone Solution...

   pmc.ncbi.nlm.nih.gov › articles › PMC8483163

   Conclusion: Spironolactone solution is an effective and well-tolerated topical treatment for mild to moderate acne vulgaris and is superior to clindamycin solution. Keywords: acne vulgaris, spironolactone, clindamycin, comedone, solution. Introduction.

6. onlinelibrary.wiley.com › doi › fullEfficacy and safety of topical spironolactone 5% cream in the...

   onlinelibrary.wiley.com › doi › full

   1 Ιουλ 2021 · In this pilot clinical trial, topical spironolactone 5% was evaluated to treat patients with mild to moderate acne twice a day for 8 weeks. The rate of improvement as any alterations in the number of open and closed comedones, facial inflammatory papules, and acne global grading scores were assessed.

7. pubmed.ncbi.nlm.nih.gov › 32078195Treatment of acne with spironolactone: a retrospective review of...

   pubmed.ncbi.nlm.nih.gov › 32078195

   PMID: 32078195. DOI: 10.1111/jdv.16302. Abstract. Background: Few large studies have assessed spironolactone treatment of adult female acne. Objectives: To explore the role of spironolactone in the treatment of adult female acne.