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6 Ιαν 2023 · Serum transferrin saturation. This test measures the amount of iron bound to the protein transferrin that carries iron in your blood. Transferrin saturation values greater than 45% are considered too high.
The best monitoring procedure is to determine transferrin saturation during therapy. Transferrin saturation in conjunction with ferritin gives a conclusive prediction of the exclusion of iron overloading in patients with chronic liver disease.
Transferrin is the iron transport protein in serum. In cases of iron deficiency, the degree of transferrin saturation appears to be an extremely sensitive indicator of functional iron depletion. The ferritin levels are depressed when there is a deficiency of storage iron.
6 Ιαν 2023 · There are a few types of hemochromatosis, but the most common type is caused by a gene change passed down through families. Only a few people who have the genes ever develop serious problems. Symptoms usually appear in midlife. Treatment includes regularly removing blood from your body.
Plasma membrane-bound transferrin receptor is released by proteolytic cleavage of the extracellular domain, resulting in the formation of a truncated soluble transferrin receptor (sTfR) that circulates freely in the blood. The concentration of sTfR is an indicator of iron status.
9 Μαρ 2022 · Transferrin saturations of less than 20% indicate iron deficiency, while transferrin saturations of more than 50% suggest iron overload. The terms transferrin saturation and iron-binding...
The transferrin saturation is the ratio of serum iron to the TIBC, expressed as a percentage. Levels fall in both iron deficiency and inflammatory anaemia. The table below summarises the changes in the various laboratory indicies in different disease states: Iron Indices.
