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8 Μαρ 2024 · Treatment. If your hypercalcemia is mild, you might not need treatment right away. You and your healthcare professional may wait to see if symptoms start or become worse. Your bones and kidneys might be checked over time to be sure they stay healthy.
8 Μαρ 2024 · Effective treatments reduce serum calcium by inhibiting bone resorption, increasing urinary calcium excretion, or decreasing intestinal calcium absorption (table 1). The optimal choice varies with the cause and severity of hypercalcemia.
7 Μαΐ 2024 · Denosumab is considered the first-line treatment for hypercalcemia of malignancy, along with bisphosphonates and hydration. This medication is a great treatment option for patients who have renal impairment and is shown to be very effective in lowering calcium levels.
Although there is no completely satisfactory way to correct severe hypercalcemia in patients with renal failure, hemodialysis is probably the safest and most reliable short-term treatment. IV phosphate (disodium phosphate or monopotassium phosphate) should be used only when hypercalcemia is life threatening and unresponsive to other methods and ...
6 Αυγ 2024 · Among all causes of hypercalcemia, primary hyperparathyroidism and malignancy are the most common, accounting for greater than 90 percent of cases (table 1). This topic will review the etiology of hypercalcemia. The clinical manifestations, diagnostic approach, and treatment are reviewed separately.
11 Φεβ 2022 · In general, effective therapies reduce serum calcium by one of three main mechanisms: increasing ECF volume and urinary calcium excretion, inhibiting bone resorption, or decreasing intestinal calcium absorption. Download chapter PDF. Similar content being viewed by others. Severe Hypercalcemia. Chapter © 2020. Hypercalcemia. Chapter © 2015.
The use of renal replacement therapy (RRT) is often necessary to correct the hypercalcemia, uremia and electrolyte disturbances related to Acute Kidney Injury (AKI). The aim of this work was to determine the etiologies and the place of RRT in treating patients with hypercalcaemic crisis.