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  1. 8 Δεκ 2023 · Medical therapy for persistent hypercalcemia is dictated by the systemic wellness of the patient, rate of rise of serum calcium concentration, and severity of hypercalcemia.

  2. In hypercalcemic dogs, neoplasia is the most common underlying diagnosis, followed by hypoadrenocorticism, primary hyperparathyroidism, and chronic renal failure. Approximately 70% of hypercalcemic dogs are also azotemic, with azotemia uncommon only in dogs with hyperparathyroidism.

  3. Goals of acute treatment of hypercalcemia include relieving symptoms, allowing diagnostic evaluation, and preventing death. It is very important to treat the underlying condition. Intravenous fluid treatment using normal saline will promote calciuresis.

  4. 9 Φεβ 2024 · The most effective treatment for hypercalcemia of malignancy is removal of the underlying neoplasm by surgery if anatomically feasible, induction of clinical remission with chemotherapy (most applicable for hypercalcemia associated with LSA), or radiation therapy.

  5. Hypercalcemia results in impaired neurological, neuromuscular and muscular function, impaired collecting tubule sensitivity to ADH, vasoconstriction of the afferent glomerular arteriole and thus reduced GFR as well as a diminished membrane stability generally.

  6. Identify and treat any treatable primary disease processes (eg, renal lymphoma and hypercalcemia) or complicating disorders (eg, urinary tract infections and ureteroliths). Pursue additional diagnostics recommended for Stage 1 CKD patients, including:

  7. The urine protein-to-creatinine ratio (UPC) was significantly lower in the T group at the end of the study compared to the C group. The tested supplement could be considered as a supportive treatment for dogs with advanced CKD. Keywords: Chronic kidney disease, Dog, Serum phosphorus, Serum bicarbonate, Dietary supplement. Introduction