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19 Μαΐ 2023 · Treatment of prostate cancer, particularly advanced prostate cancer, has dramatically changed in the past 10 years, with more men receiving intensified treatment earlier in their disease course. 65 While these additional treatments significantly improve overall survival, they also have the potential for added toxicity over longer periods of time.
In 2010, the International Society of Geriatric Oncology (SIOG) developed treatment guidelines for men with prostate cancer who are older than 70 years old. In 2013, a new multidisciplinary SIOG working group was formed to update these recommendations.
4 Ιουν 2024 · Prostate cancer treatment may be different when you’re elderly. Here’s what to know about diagnosis, treatments, and survival rates if you’re 70 or older.
Previously published SIOG guidelines on prostate cancer argued that age alone should not preclude effective treatment. Since 2014, the SIOG recommendations have been fully endorsed by the European Association of Urology (EAU) and are now referred to as the EAU/ESTRO/SIOG guidelines [5,6] .
8 Αυγ 2024 · There is ongoing debate regarding prostate cancer (PCa) screening in advanced age males, leading to treatment decisions often based on tumor staging and life expectancy. A critical gap in clinical evidence and tailored guidelines for the advanced age with PCa persists.
Androgen-deprivation therapy (ADT) remains the mainstay of first-line treatment of advanced disease. Once the disease becomes resistant to castration, docetaxel-based chemotherapy is the regulatory-approved standard of care, irrespective of age.
19 Ιουλ 2022 · Management of prostate cancer in males over the age of 70 can be complicated by the comorbidity, competing mortality, and health status issues specific to this group; in addition, there are generally limited data on the efficacy of newer treatments because older patients are underrepresented in clinical trials in prostate cancer.
