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  1. 19 Μαρ 2024 · Therapeutic Interventions in Heart Failure with Preserved Ejection Fraction. The goals of therapy for HFpEF are to reduce symptoms, improve quality of life, prevent disease progression, reduce hospitalizations, and effectively manage underlying comorbidities.

  2. 18 Σεπ 2024 · General management – For patients with heart failure with preserved ejection fraction (HFpEF), the goals of treatment are to reduce HF symptoms, increase functional status, and reduce the risk of hospital admission.

  3. 19 Απρ 2023 · Heart failure with preserved ejection fraction (HFpEF) is defined as signs and symptoms of HF with left ventricular EF (LVEF) ≥50%. Diagnosis and management of HFpEF needs multidisciplinary care involving primary care, cardiology, and HF specialists.

  4. 5 Ιουλ 2016 · This reduces soluble guanylate cyclase (sGC) activity, cyclic guanosine monophosphate (cGMP) content, and the favorable effects of protein kinase G (PKG) on cardiomyocyte stiffness and hypertrophy. HFpEF indicates heart failure with preserved ejection fraction.

  5. 16 Μαρ 2024 · Heart failure with preserved ejection fraction (HFpEF), simply put, is when a person has a diagnosis of heart failure and their left ventricular ejection fraction (LVEF) is 50% or higher.

  6. 3 Φεβ 2020 · Pathophysiology. Despite the marked differences in systolic function, patients with preserved ejection fraction and reduced ejection fraction can share the same level of functional impairment. Echocardiography is therefore vital to differentiate between them.

  7. 2 Μαρ 2018 · New therapies have been developed to interfere with the mediator pathways of HFpEF at the cellular and molecular level, including mineralocorticoid receptor antagonists, soluble guanylate cyclase stimulators, or angiotensin receptor-neprilysin inhibitors.