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  1. measure the TSH level in a blood sample. Changes in TSH can serve as an “early warning system” – often occurring before the actual level of thyroid hormones in the body becomes too high or too low. A high TSH level indicates that the thyroid gland is not making enough thyroid hormone (primary hypothyroidism). The opposite situation, in ...

  2. Reference Range SI Reference Intervals SERUM General Chemistry: Electrolytes ... Glucose Fasting: 70–100 mg/dL 3.8–5.6 mmol/L Random, non-fasting: <140 mg/dL <7.77 mmol/L ... TSH 0.4–4.0 μU/mL 0.4–4.0 mIU/L Triiodothyronine (T 3) (RIA) 100–200 ng/dL 1.5–3.1 nmol/L ...

  3. In overt primary hyperthyroidism TSH is nearly always below 0.10 mU/L. 1-4. (IIb,B) In overt primary hypothyroidism plasma TSH is always increased. 1-4 (IIb,B) In mild (subclinical) disorders, TSH will be the most sensitive indicator of failing thyroid function, and plasma FT4 and FT3 are often normal (III,B).

  4. Defining Ranges for Serum TSH. Individual’s range. • Much narrower than reference range. Lab reference range. • Defined by values in “normal” population. Target range. Goals for thyroxine treatment of specific conditions. Hypothyroidism: normalization of TSH within age-specific reference range.

  5. Low thyroid hormone levels cause the body’s functions to slow down, leading to general symptoms like dry skin, fatigue, loss of energy, and memory problems. Hypothyroidism is diagnosed by a simple blood test for thyroid-stimulating hormone (TSH).

  6. • Maternal hypothyroidism defined as TSH concentration elevated beyond upper limit of pregnancy-specific reference range. • Pregnancy-specific TSH reference range should be defined as follows: • Population / trimester-specific reference ranges for serum TSH during pregnancy should be defined by a provider’s institute / laboratory.

  7. Thyroid stimulating hormone (TSH) If Free T4 is normal. Test: T3 / T3 (Triiodothyronine), Total, Serum.

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