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T4 Normal High Low. Hypothyroidism Secondary. Low. Low. free T4 – either a free T4 (FT4) or free T4 index (FTI) – more accurately reflect how the thyroid gland is functioning when checked with a TSH. The finding of an elevated TSH and low FT4 or FTI indicates primary hypothyroidism due to disease in the thyroid gland.
28 Απρ 2018 · Low T4: due to the thyroid’s inability to produce enough T4. A normal T4 in the context of a raised TSH may suggest subclinical hypothyroidism (most commonly caused by underlying autoimmune disease). Aetiology. Causes of primary hypothyroidism include: Autoimmune thyroiditis (50%) Iodine deficiency or excess; Thyroidectomy
Measurement of Thyroid Hormones. T4: thyroxine and T3: triiodothyronine. 99.99% T4 and 99.5% T3 circulate bound to proteins. 70-80% bound to thyroxine binding globulin (TBG) 15-20% bound to albumin. 8-10% bound to transthyretin.
If the TSH level is low and the FT4 result is high this suggests an overactive thyroid (hyperthyroidism) that requires treatment. If the TSH level is slightly raised but the FT4 level is still within the normal reference range this is called subclinical hypothyroidism or mild thyroid failure.
What blood tests do health care providers use to check a person’s thyroid function? A health care provider may order several blood tests to check thyroid function, including the following: • TSH test. • T4 tests. • T3 test. • thyroid-stimulating immunoglobulin (TSI) test.
If your TSH is low and your FT4 and or FT3 are high, you have an overactive thyroid (hyperthyroidism). If your TSH is low and your FT4 and or FT3 are normal, you should repeat the test in six to12
The optimal dose of thyroxine for long-term therapy is assessed from the results of thyroid function tests together with clinical findings. In determining the optimal dose of thyroxine the biochemical target is a TSH result that is detectable, not elevated, and preferably within the reference range.