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Vitamin D promotes calcium absorption in the gut and maintains adequate serum calcium and phosphate concentrations to enable normal bone mineralization and to prevent hypocalcemic tetany (involuntary contraction of muscles, leading to cramps and spasms). It is also needed for bone growth and bone remodeling by osteoblasts and osteoclasts ...
9 Απρ 2023 · In the absence of vitamin D, approximately 10 to 15% of dietary calcium and 60% of phosphorus are absorbed. In the presence of vitamin D, this percentage of absorption is increased to 30% to 40% for calcium and 80% for phosphorus. In the kidneys, 1,25-dihydroxy vitamin promotes calcium reabsorption.
31 Δεκ 2021 · The level of vitamin D intake and achieved serum levels of 25(OH)D that are optimal and safe for skeletal health and the non-skeletal actions remain controversial, but are likely between an intake of 800-2000IU vitamin D in the diet and 20-50ng/ml 25(OH)D in the blood.
Traditionally, any well-prepared Vit. D guidelines should reflect clinical practice and therefore must include the following domains: definition of risk groups for low vitamin D; principles of evaluation of Vit. D status by using laboratory measurements; and Vit. D dosing for prevention and treatment.
17 Ιουλ 2023 · A circulating level of 25-hydroxyvitamin D greater than 30 ng/mL is required to maintain a healthy level of vitamin D. Vitamin D deficiency can lead to an array of problems, most notably rickets in children and osteoporosis in adults.
Vitamin D is a fat-soluble vitamin that depends on the gut’s ability to absorb dietary fat. People who are obese tend to have lower blood vitamin D levels. Vitamin D accumulates in excess fat tissues but is not easily available for use by the body when needed.
With all of this information collectively, most experts now agree that vitamin D deficiency should be defined as a 25(OH)D of < 20 ng/ml. Vitamin D insufficiency is now recognized as a 25(OH)D of 21-29 ng/ml.
