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Eight members of the Herpesviridae family commonly infect humans, and close to 100% of the adult population is infected with at least one of these. The five that cause the most health concerns are: herpes simplex virus (HSV) type 1 and 2, Epstein–Barr virus (EBV), cytomegalovirus (CMV), and varicella zoster virus (VZV).
- Virus reactivation: a panoramic view in human infections - PMC
The herpes simplex virus type 1 ICP0 promoter is activated...
- Virus reactivation: a panoramic view in human infections - PMC
27 Ιουν 2014 · Scientists are mystified by the mechanism that 'reactivates' dormant viruses such as herpes. Now, a new study suggests interactions with other infections may be responsible.
The herpes simplex virus type 1 ICP0 promoter is activated by viral reactivation stimuli in trigeminal ganglia neurons of transgenic mice. J Neurovirol. 2003;9:336–345. doi: 10.1080/13550280390201047.
31 Οκτ 2012 · After a flare-up, the virus usually remains latent until the right circumstances to return. Now, research sheds some light on what triggers the virus to reactivate.
23 Νοε 2019 · Researchers have now uncovered a cellular mechanism that may explain how the herpes simplex virus goes into and comes out of hiding.
1 Σεπ 2018 · Herpes simplex virus (HSV) establishes a latent infection in peripheral neurons and can periodically reactivate to cause disease. Reactivation can be triggered by a variety of stimuli that activate different cellular processes to result in increased HSV lytic gene expression and production of infectious virus.
Reactivation of latent virus causes the recurrent lesions associated with genital herpes. In addition to genital infection, HSV-2 can spread systemically to cause meningitis. More serious, however, is the intrauterine or peripartum transmission of HSV-2 from a productively infected mother to her child, which can result in encephalitis and/or ...
