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1. www.nature.com › articles › 1205996Uracil in DNA – occurrence, consequences and repair | Oncogene -...

   www.nature.com › articles › 1205996

   16 Δεκ 2002 · Uracil in DNA results from deamination of cytosine, resulting in mutagenic U : G mispairs, and misincorporation of dUMP, which gives a less harmful U : A pair. At least four different human...

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2. www.ncbi.nlm.nih.gov › pmc › articlesUracil in DNA: consequences for carcinogenesis and chemotherapy

   www.ncbi.nlm.nih.gov › pmc › articles

   9 Σεπ 2008 · Genomic uracil is removed by uracil DNA glycosylases of base excision repair (BER). Unfortunately, BER is apparently problematic during thymidylate stress. Because BER requires a DNA resynthesis step, elevated dUTP causes reintroduction of genomic uracil.

3. pubmed.ncbi.nlm.nih.gov › 20709185Uracil in DNA--its biological significance - PubMed

   pubmed.ncbi.nlm.nih.gov › 20709185

   10 Αυγ 2020 · In this paper we will review: (i) sources of the origin of uracil in DNA; (ii) some properties of the enzymes responsible for the excision of uracil and their role in the Ig diversification process, which comprises somatic hypermutation and class switch recombination; and (iii) consequences of cytosine deamination in other than the Ig loci, in ...

4. www.sciencedirect.com › science › articleUracil in DNA—Its biological significance - ScienceDirect

   www.sciencedirect.com › science › article

   1 Δεκ 2010 · Uracil existing in DNA may arise as a result of spontaneous deamination of cytosine (leading to U:G mispairing) or from incorporation of dUMP during replication in place of dTMP leading to U:A pairing.

5. www.researchgate.net › publication › 10988806_Uracil_in_DNA_-_Occurrence(PDF) Uracil in DNA - Occurrence, consequences and repair -...

   www.researchgate.net › publication › 10988806_Uracil_in_DNA_-_Occurrence

   1 Ιαν 2003 · Uracil in DNA results from deamination of cytosine, resulting in mutagenic U : G mispairs, and misincorporation of dUMP, which gives a less harmful U : A pair. At least four different human...

6. www.ncbi.nlm.nih.gov › pmc › articlesDetection of Genomic Uracil Patterns - PMC - National Center for...

   www.ncbi.nlm.nih.gov › pmc › articles

   9 Απρ 2021 · Here, we provide a summary of diverse uracil-DNA detection methods with their advantages and limitations, and discuss their results and conclusions. We detail the global quantitative U-detection methods as well as various emerging solutions for in situ uracil-DNA detection.

7. pubmed.ncbi.nlm.nih.gov › 12483510Uracil in DNA--occurrence, consequences and repair - PubMed

   pubmed.ncbi.nlm.nih.gov › 12483510

   16 Δεκ 2002 · Uracil in DNA results from deamination of cytosine, resulting in mutagenic U : G mispairs, and misincorporation of dUMP, which gives a less harmful U : A pair. At least four different human DNA glycosylases may remove uracil and thus generate an abasic site, which is itself cytotoxic and potentially mutagenic.