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1. www.nature.com › articles › 1205996Uracil in DNA – occurrence, consequences and repair | Oncogene -...

   www.nature.com › articles › 1205996

   16 Δεκ 2002 · Uracil in DNA results from deamination of cytosine, resulting in mutagenic U : G mispairs, and misincorporation of dUMP, which gives a less harmful U : A pair. At least four different human...

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2. pubmed.ncbi.nlm.nih.gov › 20709185Uracil in DNA--its biological significance - PubMed

   pubmed.ncbi.nlm.nih.gov › 20709185

   10 Αυγ 2020 · Uracil may arise in DNA as a result of spontaneous cytosine deamination and/or misincorporation of dUMP during DNA replication. In this paper we will review: (i) sources of the origin of uracil in DNA; (ii) some properties of the enzymes responsible for the excision of uracil and their role in the I ….

3. pmc.ncbi.nlm.nih.gov › articles › PMC7347158Deoxyuracil in DNA in Health and Disease - PMC

   pmc.ncbi.nlm.nih.gov › articles › PMC7347158

   High dUTP results in an elevated rate of uracil incorporation into DNA by DNA polymerase. Uracil is excised under action of BER. Excessive excision and repair of uracil leads to chromosomal fragmentation and cell death.

4. www.ncbi.nlm.nih.gov › pmc › articlesDeoxyuracil in DNA and Disease: Genomic Signal or Managed...

   www.ncbi.nlm.nih.gov › pmc › articles

   Overview of factors that influence uracil accumulation in DNA. The presence of uracil in DNA results from spontaneous chemical deamination of cytosine, or enzymatic and metabolic processes governed by the expression, localization, and activity of several enzymes that ether catalyze cytosine deamination or generate biosynthetic intermediates in ...

5. www.researchgate.net › publication › 10988806_Uracil_in_DNA_-_Occurrence(PDF) Uracil in DNA - Occurrence, consequences and repair -...

   www.researchgate.net › publication › 10988806_Uracil_in_DNA_-_Occurrence

   1 Ιαν 2003 · Uracil in DNA results from deamination of cytosine, resulting in mutagenic U : G mispairs, and misincorporation of dUMP, which gives a less harmful U : A pair. At least four different human...

6. www.sciencedirect.com › science › articleUracil in DNA—Its biological significance - ScienceDirect

   www.sciencedirect.com › science › article

   1 Δεκ 2010 · Uracil existing in DNA may arise as a result of spontaneous deamination of cytosine (leading to U:G mispairing) or from incorporation of dUMP during replication in place of dTMP leading to U:A pairing.

7. pubmed.ncbi.nlm.nih.gov › 32398439Deoxyuracil in DNA in health and disease - PubMed

   pubmed.ncbi.nlm.nih.gov › 32398439

   This review addresses diseases that are linked to uracil accumulation in DNA, its causes, consequences, and the associated biomarkers of risk factors. Recent findings: Elevated genomic uracil is associated with megaloblastic anemia, neural tube defects, and retroviral immunity.