Αποτελέσματα Αναζήτησης
10 Αυγ 2020 · Uracil may arise in DNA as a result of spontaneous cytosine deamination and/or misincorporation of dUMP during DNA replication. In this paper we will review: (i) sources of the origin of uracil in DNA; (ii) some properties of the enzymes responsible for the excision of uracil and their role in the I ….
- Uracil in DNA: consequences for carcinogenesis and chemotherapy
Genomic uracil is removed by uracil DNA glycosylases of base...
- Uracil in DNA: consequences for carcinogenesis and chemotherapy
16 Δεκ 2002 · Uracil in DNA results from deamination of cytosine, resulting in mutagenic U : G mispairs, and misincorporation of dUMP, which gives a less harmful U : A pair. At least four different human DNA...
3 Μαρ 2011 · Uracil is well known as one of the bases used in RNA, but why is it not used in DNA – or is it? Angéla Békési and Beáta G Vértessy investigate. Thymine versus uracil. Our genetic information is stored in the form of DNA, using a four-letter alphabet.
Thymine versus uracil. Our genetic information is stored in the form of DNA, using a four-letter alphabet. The four ‘letters’ correspond to the four chemical bases that each building block of DNA – called a nucleotide – can have: adenine (A), thymine (T), cytosine (C) and guanine (G; see Figure 1 on page 28).
9 Σεπ 2008 · Genomic uracil is removed by uracil DNA glycosylases of base excision repair (BER). Unfortunately, BER is apparently problematic during thymidylate stress. Because BER requires a DNA resynthesis step, elevated dUTP causes reintroduction of genomic uracil.
1 Ιαν 2003 · Uracil in DNA results from deamination of cytosine, resulting in mutagenic U : G mispairs, and misincorporation of dUMP, which gives a less harmful U : A pair. At least four different human...
1 Δεκ 2010 · In this paper we will review: (i) sources of the origin of uracil in DNA; (ii) some properties of the enzymes responsible for the excision of uracil and their role in the Ig diversification process, which comprises somatic hypermutation and class switch recombination; and (iii) consequences of cytosine deamination in other than the Ig loci, in ...
