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1. www.nature.com › articles › 1205996Uracil in DNA – occurrence, consequences and repair | Oncogene -...

   www.nature.com › articles › 1205996

   16 Δεκ 2002 · Uracil in DNA results from deamination of cytosine, resulting in mutagenic U : G mispairs, and misincorporation of dUMP, which gives a less harmful U : A pair. At least four different human DNA...

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2. pubmed.ncbi.nlm.nih.gov › 20709185Uracil in DNA--its biological significance - PubMed

   pubmed.ncbi.nlm.nih.gov › 20709185

   10 Αυγ 2020 · In this paper we will review: (i) sources of the origin of uracil in DNA; (ii) some properties of the enzymes responsible for the excision of uracil and their role in the Ig diversification process, which comprises somatic hypermutation and class switch recombination; and (iii) consequences of cytosine deamination in other than the Ig loci, in ...

3. pmc.ncbi.nlm.nih.gov › articles › PMC5474181Mechanisms of DNA damage, repair and mutagenesis - PMC

   pmc.ncbi.nlm.nih.gov › articles › PMC5474181

   At least five major DNA repair pathways—base excision repair (BER), nucleotide excision repair (NER), mismatch repair (MMR), homologous recombination (HR) and non-homologous end joining (NHEJ)—are active throughout different stages of the cell cycle, allowing the cells to repair the DNA damage.

4. www.sciencedirect.com › science › articleUracil in DNA—Its biological significance - ScienceDirect

   www.sciencedirect.com › science › article

   1 Δεκ 2010 · In this paper we will review: (i) sources of the origin of uracil in DNA; (ii) some properties of the enzymes responsible for the excision of uracil and their role in the Ig diversification process, which comprises somatic hypermutation and class switch recombination; and (iii) consequences of cytosine deamination in other than the Ig loci, in ...

5. www.ncbi.nlm.nih.gov › pmc › articlesUracil in DNA: consequences for carcinogenesis and chemotherapy

   www.ncbi.nlm.nih.gov › pmc › articles

   9 Σεπ 2008 · Among the potential sources of DNA damage, uracil misincorporation into DNA and its removal by base excision repair (BER) has been the most commonly presumed source.

6. www.researchgate.net › publication › 10988806_Uracil_in_DNA_-_Occurrence(PDF) Uracil in DNA - Occurrence, consequences and repair -...

   www.researchgate.net › publication › 10988806_Uracil_in_DNA_-_Occurrence

   1 Ιαν 2003 · Uracil in DNA results from deamination of cytosine, resulting in mutagenic U : G mispairs, and misincorporation of dUMP, which gives a less harmful U : A pair. At least four different human DNA...

7. www.ncbi.nlm.nih.gov › pmc › articlesDetection of Genomic Uracil Patterns - PMC - National Center for...

   www.ncbi.nlm.nih.gov › pmc › articles

   9 Απρ 2021 · Three different routes can result in genomic uracil, two of which do not require specific enzymes: spontaneous cytosine deamination due to the inherent chemical reactivity of living cells, and thymine-replacing incorporation upon nucleotide pool imbalances.