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  1. 11 Αυγ 2021 · The ECS comprises a vast network of chemical signals and cellular receptors that are densely packed throughout our brains and bodies. The "cannabinoid" receptors in the brain — the CB1 receptors — outnumber many of the other receptor types on the brain.

  2. 26 Απρ 2005 · Abstract. Marijuana and its major psychotropic component, Δ 9 -tetrahydrocannabinol, stimulate appetite and increase body weight in wasting syndromes, suggesting that the CB 1 cannabinoid...

  3. The endocannabinoid system (ECS) is a signalling cascade consisting of CB1 and CB2 receptors, and enzymes for the synthesis and degradation of endogenous ligands for these receptors. Central CB1 receptors have been most widely studied since they play key roles in energy homeostasis and rimonabant, a …

  4. 11 Ιουλ 2022 · Amongst other functions, endocannabinoids control brain functions to increase food intake (particularly palatable and energy-rich) and regulate bioenergetic functions such as mitochondria ...

  5. Endocannabinoids and cannabinoid CB1 receptors are known to play a generalized role in energy homeostasis. However, clinical trials with the first generation of CB1 blockers, now discontinued due to psychiatric side effects, were originally designed to reduce food intake and body weight rather than the metabolic risk factors associated with ...

  6. 19 Ιαν 2023 · The endocannabinoid system (eCB) has been studied to identify the molecular structures present in Cannabis sativa. eCB consists of cannabinoid receptors, endogenous ligands, and the associated enzymatic apparatus responsible for maintaining energy homeostasis and cognitive processes.

  7. The endocannabinoid system is a lipid signaling system consisting of specific cannabinoid receptors (CB 1 and CB 2 receptors), endogenous ligands (mainly anandamide and 2-arachidonoylglycerol), and a battery of enzymes responsible for the synthesis and degradation of the ligands.