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1. www.ncbi.nlm.nih.gov › books › NBK537009Ethylene Glycol Toxicity - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK537009

   26 Σεπ 2022 · Fomepizole is the antidote for toxic alcohols, and it acts by inhibiting alcohol dehydrogenase to cease toxic alcohol metabolism. Ethanol may also be utilized therapeutically to inhibit alcohol dehydrogenase when fomepizole is unavailable.

2. emedicine.medscape.com › article › 814701-treatmentEthylene Glycol Toxicity Treatment & Management - Medscape

   emedicine.medscape.com › article › 814701-treatment

   • Αποθηκευμένο αντίγραφο

   Fomepizole (Antizol) is a convenient antidotal therapy for treatment of ethylene glycol or methanol intoxication. Fomepizole received US Food and Drug Administration (FDA) approval for use in...

3. www.aafp.org › pubs › afpTreatment of Ethylene Glycol Poisoning - AAFP

   www.aafp.org › pubs › afp

   • Αποθηκευμένο αντίγραφο

   1 Σεπ 2002 · Ethylene glycol poisoning should be suspected in an intoxicated patient with anion gap acidosis, hypocalcemia, urinary crystals, and nontoxic blood alcohol concentration. Fomepizole is a...

4. www.medscape.com › viewarticle › 757588_2Antidotes for Toxicological Emergencies: A Practical Review -...

   www.medscape.com › viewarticle › 757588_2

   The use of ethanol or, preferably, fomepizole for alcohol dehydrogenase (ADH) inhibition is a mainstay in the management of toxicity due to ingestion of methanol, ethylene glycol, or...

5. www.njmonline.nl › getpdfethylene glycol or methanol intoxication: which antidote should...

   www.njmonline.nl › getpdf

   Ethylene glycol (EG) and methanol poisoning can cause life-threatening complications. Toxicity of EG and methanol is related to the production of toxic metabolites by the enzyme alcohol dehydrogenase (ADH), which can lead to metabolic acidosis, renal failure (in EG poisoning), blindness (in methanol poisoning) and death.

6. www.nejm.org › doi › fullToxic Alcohols | New England Journal of Medicine

   www.nejm.org › doi › full

   17 Ιαν 2018 · Poisonings by the toxic alcohols (methanol, ethylene glycol, isopropanol, diethylene glycol, and propylene glycol) are potentially fatal. This review summarizes the mechanisms of...

7. bpspubs.onlinelibrary.wiley.com › doi › fullAntidotes for poisoning by alcohols that form toxic metabolites

   bpspubs.onlinelibrary.wiley.com › doi › full

   9 Νοε 2015 · Guidelines suggest that fomepizole should be the main antidote for methanol or ethylene glycol poisoning 37, 38, while ethanol can be used when fomepizole is unavailable.