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17 Απρ 2023 · Iron is an essential element of various metabolic processes in humans, including DNA synthesis, electron transport, and oxygen transport. Unlike other minerals, iron levels in the human body are controlled only by absorption.
Iron is required for the production of red blood cells (a process known as haematopoiesis), but it's also part of haemoglobin (that is the pigment of the red blood cells) binding to the oxygen and thus facilitating its transport from the lungs via the arteries to all cells throughout the body.
1 Φεβ 2014 · Iron is an essential element for almost all living organisms as it participates in a wide variety of metabolic processes, including oxygen transport, deoxyribonucleic acid (DNA) synthesis, and...
I. Introduction. Iron has several vital functions in the body. It serves as a carrier of oxygen to the tissues from the lungs by red blood cell haemoglobin, as a transport medium for electrons within cells, and as an integrated part of important enzyme systems in various tissues.
25 Οκτ 2017 · Iron binds to plasma TF and is distributed to tissues throughout the body. Quantitatively, most iron is used by immature red blood cells in the bone marrow for hemoglobin production. Senescent erythrocytes are phagocytosed by macrophages, and the iron is released from catabolized hemoglobin and re-enters the circulation.
18 Απρ 2023 · In this chapter, the basic biochemistry of iron is presented. After introducing the most important molecules involved, such as myoglobin, hemoglobin, ferritin and transferrin, the various classes of iron enzymes are described.
Cellular iron homeostasis is maintained by iron and heme transport proteins that work in concert with ferrireductases, ferroxidases, and chaperones to direct the movement of iron into, within, and out of cells. Systemic iron homeostasis is regulated by the liver-derived peptide hormone, hepcidin.
