Αποτελέσματα Αναζήτησης
15 Φεβ 2021 · Platelet Morphology. Platelets are very small non-nucleated cells with fine granules that derive from fragmentation of megakaryocytes.
Platelets are very small blood cells (1.5-3 μm), which play a major role in primary haemostasis and in coagulation mechanisms. Platelet characterization requires their counting (see Chapter 15 ) associated with accurate morphology analysis.
Platelets change shape with activation as a result of a complex reorganization of the platelet membrane skeleton and cytoskeleton. With activation, platelets undergo release of α-granules, dense bodies, and lysosomes, the contents of which work to restore vascular integrity.
This review summarizes the physiological and pathological features of platelet size and morphology, circulating megakaryocytes, micromegakaryocytes and megakaryoblasts, and provides an overview of current guidelines on the reporting of platelet morphology.
14 Νοε 2022 · Platelets circulate in the blood in discoid form but undergo significant structural changes following activation, mediated by actin and myosin within the cytoplasm. The platelets transform from discoid forms into compact spheres with dendritic extensions, which allow platelet adhesion.
9 Μαρ 2017 · In order to better understand how platelets function, it is essential to have insight into their overall morphology and (ultra)structure. This chapter will contribute to this and present our current view of the platelet structure and physiology in health and disease and the recent techniques available to visualize this.
Overall Morphology and Function of Platelets. Blood platelets are small anucleate cell fragments that, together with the red blood cells, are the most abundant cells in the circulation.
