Αποτελέσματα Αναζήτησης
Confronted with a low serum testosterone level, physi-cians should not jump to the diagnosis of hypogonadism, as confirmation and thorough evaluation are warranted before making the diagnosis or starting therapy. This review discusses how to approach the finding of a low testosterone value, stressing the need to confirm the
Symptoms must be accompanied by decreased serum concentrations of total testosterone (TT) or free T level to support a diagnosis of symptomatic hypogonadism (Level 2, Grade A).
At each visit, clinicians should specifically monitor for symptomatic improvement, treatment modality-specific adverse effects, serum total and free testosterone levels, serum hematocrit, and in those men identified at increased risk, DRE, PSA testing, and evaluation of LUTS should be performed.
The presence of symptoms alone does not constitute testosterone deficiency. Symptoms must be accompanied by decreased serum concentrations of total testosterone (TT) or free T level to support a diagnosis of symptomatic TD.
1 Ιουλ 2022 · Accurate measurement of total and free testosterone is essential for making the diagnosis of androgen disorders. Total testosterone should ideally be measured in a fasting state in the morning using a reliable assay, such as liquid chromatography tandem mass spectrometry, in a laboratory that is certified by an accuracy-based benchmark.
Testosterone secretion has diurnal variation and is suppressed post-prandially, so serum testosterone and sex-hormone binding globulin (SHBG) should be measured between 7.00 am–11.00 am following an overnight fast. Most testosterone is protein-bound in the circulation and the unbound free testosterone (FT) represents only 2–4% of the total.
8 Φεβ 2022 · Measure serum free testosterone using an accurate and reliable method in patients who have conditions that alter sex hormone–binding globulin (SHBG) or if serum total testosterone concentrations are near the lower limit of the normal adult male reference range.
