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This model of the sequence of brain development has led toward many fruitful lines of investigation in neuroscience. Among other things, it can explain well-known birth defects of the brain or the nervous system in terms of the stage at which development was disturbed.
17 Δεκ 2018 · The excitatory and inhibitory neurons within the cerebellum originate from different distinct germinal zones and migrate through complex routes to assemble in a well-defined neuronal organization in the cerebellar cortex and nuclei.
Overall, both GnRH I and II are widely expressed within the human brain. As expected based on traditional understanding of the role of GnRH in the HPG axis, GnRH I is highly expressed in the hypothalamus, especially the arcuate nucleus.
The incredible diversity of neurons in the brain results from regulated neurogenesis during embryonic development. During the process, neural stem cells differentiate—that is, they become any one of a number of specialised cell types—at specific times and regions in the brain.
15 Φεβ 2023 · With 16 billion neurons, the human cerebral cortex contains a larger number of neurons than that of our closest relative, the chimpanzee (6 billion neurons), or the more distantly related rhesus...
28 Οκτ 2021 · These observations provide strong evidence that myelination can occur in the absence of neuronal activity and glutamate signaling—or neuronal signaling at all.
There has been a longstanding notion, based on comparisons between vertebrate species, that increased numbers of glial cells in the brain correlate with, and possibly contribute to, superior intelligence. As discussed in the section 2.5.2, the relationships between brain size, neuron number, and intelligence are still controversial.
