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Biotin, an essential micronutrient for all mammals, is a mem-ber of the B complex group of vitamins. Biotin was discovered in nutritional experiments that revealed a factor in many food-stuffs that was capable of curing the scaly dermatitis, hair loss, and neurologic signs induced in rats fed dried egg whites.
As mentioned earlier humans are exposed to two sources of biotin, the first being the dietary source, and the second being the bacterial source in the large intestine (Wrong et al. 1981).
18 Φεβ 2009 · Biotin is a water-soluble vitamin and serves as a coenzyme for five carboxylases in humans. Biotin is also covalently attached to distinct lysine residues in histones, affecting chromatin...
1 Αυγ 2012 · Biotin was initially discovered in 1927 in raw egg white, where it is bound to the protein avidin [1].
Biotin was initially discovered in 1927 in raw egg white, where it is bound to the protein avidin [1]. Even though it has been identified as a necessary nutrient for almost a century, it has only begun to be understood since the beginning of the twenty-first century.
BACKGROUND INFORMATION. After biotin's initial discovery in 1927 (Boas, 1927), it took nearly 40 years of research for it to be fully recognized as a vitamin. In mammals this colorless, water-soluble vitamin functions as a cofactor for enzymes that catalyze carboxylation retentions (Dakshinamurti, 1994). Function.
23 Οκτ 2012 · Since its discovery at the beginning of the 20th century, biotin has been shown to be a prosthetic group for several enzymes. This vitamin is involved in the regulation of fatty acid synthesis and it also influences the carbohydrate metabolism.
