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3 Φεβ 2016 · Given the challenge facing emergency physicians managing life-threatening acute AE with airway compromise, we investigated the use of FFP to examine its ability to prevent intubation and shorten the course of airway angioedema and hence ICU stays.
Risks with the use of FFP include potential for initial worsening of angioedema (specifically in hereditary angioedema due to its bradykinin content), viral transmission, delayed administration time, allergic/transfusion reactions, and volume overload .
1 Ιαν 2016 · Angioedema (AE) is a common condition which can be complicated by laryngeal edema, having up to 40% mortality. Although sporadic case reports attest to the benefits of fresh frozen plasma (FFP)...
3 Φεβ 2016 · In an emergency department setting, the use of FFP should be considered in managing acute airway nonhereditary AE (refractory to steroid, antihistamine, and epinephrine) and larger prospective, better controlled studies are needed to devise appropriate treatment guidelines. Expand. [PDF] Semantic Reader. Save to Library. Create Alert. Cite.
Angioedema (AE), defined as self-limited, localized swelling, can manifest as an acute attack of asymmetric, nonpruritic, nonpitting subcutaneous or submucosal edema [1]. The reported prevalence varies, depending on etiology, popula-tion studied, and method of study (self-reported versus med-ically diagnosed).
11 Αυγ 2020 · This is the first time the successful treatment of hereditary angioedema with FFP has been reported from Pakistan. In the absence of targeted therapy in most LMICs, FFP is an alternative therapeutic option for the acute management of HAE.
FFP has been shown to be of benefit in hereditary angioedema, in which its main action is to replace the deficient C1 esterase inhibitor.
