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Aging is a puzzling phenomenon for the theory of evolution by natural selection. The basic intuition of Darwin was that adaptation could be explained by the enhanced survival rates of individuals with heritable attributes that fostered survival and reproduction.
Aging, or senescence as it is sometimes called, is an inevitable progressive deterioration of physiological function with increasing age, demographically characterized by an age-dependent...
Only a few broad, overarching theories attempt to explain why we and nearly all living organisms age. These theories compete with each other, making it unlikely that more than one of them could be true. Over time, some theories have fallen out of favor as others have become more widely accepted.
Evolutionary theory predicts that aging is an inevitable result of the increased selective impact of genes that influence early-life survival and fecundity compared with genes that act late in life [1–3].
The evolutionary theory of aging has set the foundations for a comprehensive understanding of aging. The biology of aging has listed and described the “hallmarks of aging,” i.e., cellular and molecular mechanisms involved in human aging.
9 Νοε 2000 · The evolutionary theory of ageing explains why ageing occurs, giving valuable insight into the mechanisms underlying the complex cellular and molecular changes that contribute to...
18 Ιουλ 2018 · In this review, we discuss what can be learned about aging by considering its evolutionary biology, and how evolutionary thinking could help inform practical measures to ameliorate the effects of human aging.
