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25 Ιαν 2017 · In 1953, James Watson and Francis Crick revealed the double helical structure of DNA using the results of Rosalyn Franklin obtained by X-ray scattering on natural filaments formed by DNA molecules [1]. Proteins, the nanomachines essential to living organisms, have their “manufacturing plan” encoded in their DNA gene sequence [2].
This diffraction photo of hydrated sodium thymonucleate (DNA) provided crucial evidence supporting the double helix DNA structure proposed by James Watson and Francis Crick (Cavendish Laboratory, Cambridge University) based on published chemical clues and a physical molecular model they constructed.
1 Ιουν 2011 · X-ray crystallography is an imaging technique that uses x-ray diffraction to evaluate the molecular structure of a crystalline solid. This article discusses the critical role played by x-ray crystallography in the elucidation of the structure of DNA.
25 Ιαν 2017 · In benchmark tests on a set of 6,311 X-ray diffraction images, the proposed CNN achieved between 87% and 99% accuracy depending on the type of anomaly.
1 Φεβ 2018 · Rosalind Franklin used X-ray diffraction to determine the structure of DNA molecules. One of her best X-ray pictures is numbered Photo 51 and is shown in Fig. 1(a). This photo was instrumental to J. D. Watson and F. Crick in deducing the double-helix model of DNA.
1 Μαΐ 2007 · A step-by-step method of teaching the X-ray diffraction analysis of DNA using the approach employed by James Watson, Francis Crick, Maurice Wilkins, Rosalind Franklin, and Raymond Gosling at an upper undergraduate and graduate level is described.
28 Αυγ 2015 · The structure of DNA was determined in 1953 by x-ray fiber diffraction. Several attempts have been made to obtain a direct image of DNA with alternative techniques. The direct image is intended to allow a quantitative evaluation of all relevant characteristic lengths present in a molecule.