Αποτελέσματα Αναζήτησης
This diffraction photo of hydrated sodium thymonucleate (DNA) provided crucial evidence supporting the double helix DNA structure proposed by James Watson and Francis Crick (Cavendish Laboratory, Cambridge University) based on published chemical clues and a physical molecular model they constructed.
25 Ιαν 2017 · Biological crystallography, the main method of structural biology, which is the branch of biology that studies the structure and spatial organization in biological macromolecules, is based on the study of X-ray diffraction by crystals of macromolecules.
1 Μαΐ 2007 · A step-by-step method of teaching the X-ray diffraction analysis of DNA using the approach employed by James Watson, Francis Crick, Maurice Wilkins, Rosalind Franklin, and Raymond Gosling at an upper undergraduate and graduate level is described.
1 Φεβ 2018 · Rosalind Franklin used X-ray diffraction to determine the structure of DNA molecules. One of her best X-ray pictures is numbered Photo 51 and is shown in Fig. 1 (a). This photo was instrumental to J. D. Watson and F. Crick in deducing the double-helix model of DNA.
Photo 51 is an X-ray based fiber diffraction image of a paracrystalline gel composed of DNA fiber [1] taken by Raymond Gosling, [2] [3] a postgraduate student working under the supervision of Maurice Wilkins and Rosalind Franklin at King's College London, while working in Sir John Randall's group.
The early x-ray diffraction results indicated that DNA was composed of two strands of the polymer wound into a helix. The observation that DNA was double-stranded was of crucial significance and provided one of the major clues that led to the Watson-Crick structure of DNA.
18 Μαΐ 2011 · In the present article, we show how X-ray diffraction from oriented non-crystalline aggregates (fiber diffraction) may be utilized for characterizing sequence-related variations in DNA structure and for evaluating the relationship between DNA structure and interactions.
