Αποτελέσματα Αναζήτησης
26 Ιαν 2021 · Does zinc sulfate prevent therapy-induced taste alterations in head and neck cancer patients? Results of phase III double-blind, placebo-controlled trial from the North Central Cancer Treatment Group (N01C4).
In this review, we summarize the recent epidemiological, experimental, and clinical findings of zinc dyshomeostasis in cancer, and outline the potential clinical applications of zinc in cancer prevention, diagnosis, and therapy.
The patients treated with zinc were mainly diagnosed with head and neck cancer and underwent chemo-, radio- or concurrent radio-chemotherapy. Interventions included the intake of different amounts of zinc supplements and oral zinc rinses.
The decrease in zinc is due to the down regulation of the ZIP-family zinc uptake transporter. These cells are as "ZIP-deficient/decreased zinc" malignancies. This provides a target for a chemotherapy that can restore the high zinc levels that will manifest cytotoxic effects in the malignant cells.
Zinc shows incredible toxicity toward cancer cells without showing any side effects toward healthy cells. It is recommended that zinc be added to cancer treatment regimens to alleviate zinc deficiency in cancer patients and perhaps to treat cancer as a whole.
1 Ιουλ 2022 · This reveals other uses, especially for the treating approach of oral mucositis and taste disorders in carcinoma cases undergoing radiation therapy and therapy with the use of chemical substances. The outcomes suggested on effectiveness more specifically support the inflammation resistance and oxidation resistance mechanisms of ZnC.
2 Σεπ 2023 · Clinically, it would be beneficial to explore the relationship between serum zinc levels and local zinc concentrations in patients with cancer, as well as the reliability of serum zinc levels as a biomarker of carcinogenesis risk and cancer patient prognosis.
