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  1. Το μπεμπεδοϊκό οξύ είναι ένας αναστολέας της αδενοσινοτριφωσφορικής κιτρικής λυάσης (ACL) που μειώνει τη χοληστερόλη των λιποπρωτεϊνών χαµηλής πυκνότητας (LDL-C) μέσω αναστολής της σύνθεσης της χοληστερόλης στο ήπαρ.

  2. Bempedoic acid is a medication for high blood cholesterol levels that blocks an enzyme in the liver. It is approved in the US and the EU, and can be used with or without statins.

  3. 25 Ιουλ 2024 · Bempedoic acid (Nexletol) is a non-statin cholesterol-lowering medicine that may reduce the risk of heart attack and heart procedures. Learn about its side effects, interactions, cost, and how to take it safely.

  4. 10 Αυγ 2020 · Bempedoic acid is a new class of nonstatin LDL-lowering therapy that, like statins, targets the cholesterol biosynthesis pathway in the liver. 3 Whereas statins inhibit HMG CoA reductase, bempedoic acid inhibits ATP-citrate lyase (ACL), two steps upstream of HMG CoA reductase. 3 Unlike statins, bempedoic acid is administered as a prodrug and is ...

  5. 26 Σεπ 2023 · Bempedoic acid is a prescription medicine that lowers LDL-C (bad cholesterol) in adults with high cholesterol or heart disease. It works by blocking an enzyme in the liver and is used with other lipid-lowering medicines, but not with statins.

  6. 28 Φεβ 2024 · Bempedoic acid is a lipid-lowering agent pivotal in managing patients with elevated low-density lipoprotein cholesterol (LDL-C) levels.

  7. 1 Φεβ 2024 · Bempedoic acid is used together with diet and other cholesterol-lowering medicines to reduce bad cholesterol (LDL) in patients with primary hyperlipidemia (high blood cholesterol), including heterozygous familial hypercholesterolemia (HeFH).

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