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11 Μαρ 2024 · Metabolic alkalosis, a disorder that elevates the serum bicarbonate, can result from several mechanisms: intracellular shift of hydrogen ions; gastrointestinal loss of hydrogen ions; excessive renal hydrogen ion loss; administration and retention of bicarbonate ions; or volume contraction around a constant amount of extracellular bicarbonate ...
- Polak A, Haynie Gd, Hays Rm, Schwartz Wb. Effects of Chronic Hypercapnia on Electrolyte and Acid-Base Equilibrium. I. Adaptation. J Clin Invest 1961; 40:1223
Medline ® Abstract for Reference 24 of 'Causes of metabolic...
- Polak A, Haynie Gd, Hays Rm, Schwartz Wb. Effects of Chronic Hypercapnia on Electrolyte and Acid-Base Equilibrium. I. Adaptation. J Clin Invest 1961; 40:1223
5 Μαΐ 2022 · The pathogenesis of metabolic alkalosis involves either a loss of fixed acid or a net accumulation of bicarbonate within the extracellular fluid. The loss of acid may be via the gastrointestinal tract or the kidney, whereas the sources of excess alkali may be via oral or parenteral alkali intake.
17 Ιουλ 2023 · There is a multitude of disease states that induce metabolic alkalosis. In general, the causes can be narrowed down to an intracellular shift of hydrogen ions, gastrointestinal (GI) loss of hydrogen ions, excessive renal hydrogen ion loss, retention or addition of bicarbonate ions, or volume contraction around a constant amount of extracellular ...
Metabolic alkalosis occurs when digestive issues disrupt the blood’s acid-base balance. It can also be due to conditions affecting the liver, kidneys or heart. Metabolic alkalosis is usually not life-threatening. It does not have lingering effects on your health once it is treated.
Metabolic alkalosis is a very commonly encountered acid-base disorder that may be generated by a variety of exogenous and/or endogenous, pathophysiologic mechanisms. Multiple mechanisms are also responsible for the persistence, or maintenance, of metabolic alkalosis.
Metabolic alkalosis is bicarbonate (HCO 3 −) accumulation due to acid loss, alkali administration, intracellular shift of hydrogen ion, or renal HCO 3 − retention. The most common causes are volume depletion (particularly when involving loss of gastric acid and chloride (Cl) due to recurrent vomiting or nasogastric suction) and diuretic use.
6 Νοε 2019 · Metabolic. Excess loss of hydrogen ion —this occurs primarily due to gastric losses (prolonged and severe gastric aspiration, excessive emesis of gastric contents as in pyloric stenosis, congenital chloridorrhea). [2] [3]
