Αποτελέσματα Αναζήτησης
Asacol 400 mg, Γαστρανθεκτικά δισκία. Το πηγαίο έγγραφο είναι διαθέσιμο προς ανάγνωση ή μεταφόρτωση από τους συνδρομητές.
25 Μαρ 2024 · Advise women who are pregnant, breastfeeding, or of childbearing potential that Asacol contains dibutyl phthalate, which was associated with malformations and adverse effects on the male reproductive system in animal studies.
7 Μαρ 2014 · However, dibutyl phthalate (DBP) is an inactive ingredient in Asacol’s enteric coating, and in animal studies at doses >190 times the human dose based on body surface area, maternal DBP was associated with external and skeletal malformations and adverse effects on the male reproductive system.
Dibutyl phthalate (DBP) is an endocrine disruptor and used in some medication coatings, such as mesalamine for treatment inflammatory bowel disease (IBD). Objectives: To determine whether high-DBP from some mesalamine medications alters thyroid function.
CLINICAL PHARMACOLOGY. Mesalamine is thought to be the major therapeutically active part of the sulfasalazine molecule in the treatment of ulcerative colitis. Sulfasalazine is converted to equimolar amounts of sulfapyridine and mesalamine by bacterial action in the colon.
27 Αυγ 2019 · Asacol® and Asacol® HD’s active ingredient is mesalamine, that uses DBP as an excipient in the enteric coating, while numerous other mesalamine formulations, such as Pentasa®, Lialda®, or ...
17 Φεβ 2020 · Asacol HD (product formulated without dibutyl phthalate [DBP]): Administer on an empty stomach (at least 1 hour before or 2 hours after a meal). Asacol HD (product formulated with DBP), Asacol 800 [Canadian product]: Administer with or without food.
