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  1. 28 Σεπ 2023 · Treatment. If the disease progresses slowly, causes no pain and has little impact on your ability to use your hands for everyday tasks, you might not need treatment. Instead, you can wait to see if Dupuytren contracture progresses.

  2. 17 Σεπ 2023 · As some new treatments have offered a less-invasive way to manage Dupuytren's contracture, there are some healthcare providers who now recommend early treatment. With collagenase injections and needle aponeurotomy, repeat treatment is not as much of a concern.

  3. 3 Μαΐ 2022 · Researchers at the Kennedy Institute, University of Oxford, led by Professor Jagdeep Nanchahal have demonstrated the efficacy of the anti-TNF drug adalimumab for patients with early stage Dupuytren’s disease.

  4. Conservative treatments for Dupuytren contracture include: Physical therapy or stretching exercises. Bracing or splinting to stretch your fingers to their usual range of motion (how far you can move them).

  5. 27 Ιαν 2022 · Operative treatments include percutaneous needle fasciotomy (PNF), open fasciotomy (OF), Clostridium collagenase histolyticum (CCH) injections, limited fasciectomy (LF) and dermofasciectomy (DF). The various methods of DD treatment are reviewed. Results: We summarize the highlights of each treatment option as well as the strengths and weaknesses.

  6. 14 Ιουλ 2023 · Percutaneous needle fasciotomy and collagenase injections are significant therapeutic alternatives to surgery. Definition. An inherited disease of progressive fibrous tissue contracture of the palmar fascia, Dupuytren's contracture is seen predominantly in men of northern European descent aged >40 years.

  7. 26 Φεβ 2023 · Dupuytren disease is predominantly a myofibroblastic disease that affects the palmar and digital fascia of the hand and results in contracture deformities. The most commonly affected digits are the fourth (ring) and fifth (small or pinky) digits.

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