Αποτελέσματα Αναζήτησης
Gene therapy is a therapeutic strategy using genetic engineering techniques to treat various diseases. 1,2) In the early 1960s, gene therapy first progressed with the development of recombinant DNA (rDNA) technology, 1) and was further developed using various genetic engineering tools, such as viral vectors. 3–5) More than 1900 clinical ...
Gene therapy is an intervention in which a defective gene is repaired in vivo, or a gene product is delivered to target cells by a clinically safe vehicle. The procedures of gene therapy aim to restore the function of a defective gene or replace a mutant gene with a paralogous gene.
30 Μαΐ 2022 · The use of genetic engineering to introduce transgenic or artificial genes into therapeutic cells has been pursued for decades as a means to create safer and more effective cell-based products.
Targeted nucleases have provided researchers with the ability to manipulate virtually any genomic sequence, enabling the facile creation of isogenic cell lines and animal models for the study of human disease, and promoting exciting new possibilities for human gene therapy.
3 Ιαν 2020 · In the 1970s, the development of genetic engineering (manipulation of DNA or RNA) established a novel frontier in genome editing. 1 Based on engineered or bacterial nucleases, genome editing...
1 Ιαν 2018 · Research advances in the fields of genetics, molecular biology, clinical medicine, and human genomics has led to the development of the new stream of gene therapy. It involves the transfer of healthy genes into cells with faulty genes, of an individual to treat or prevent a disease.
15 Απρ 2021 · Gene-based therapies are an important avenue for achieving a possible cure. Focused research in the last three decades has provided significant clues to optimize the potential of cancer...
